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  • Caverject = Injections in the Penis for Impotence

    Doctor steve

    is it possible to be using caverject too long? as a first gulf war veteran i was injured in the groin area and deemed impotent. Caverject has been a god send, hwoever i am worried that the decade long use of caverject may be effecting the penis, it is starting to show slight signs of distortion when erect, I change injection sites with regularity and been using caverject about 2 times a month for about 11 years or so.

    the va and their medical programs suck ass and I am unable to see the urologist again until early 2009

  • #2
    Originally posted by watson View Post
    Doctor steve

    is it possible to be using caverject too long? as a first gulf war veteran i was injured in the groin area and deemed impotent. Caverject has been a god send, hwoever i am worried that the decade long use of caverject may be effecting the penis, it is starting to show slight signs of distortion when erect, I change injection sites with regularity and been using caverject about 2 times a month for about 11 years or so.

    the va and their medical programs suck ass and I am unable to see the urologist again until early 2009

    Caverject, to get everyone on the same page, is an injectable medication for the treatment of impotence. It really, really, works...and it had better, considering you have to inject it into the base of the penis:



    The signs of distortion you mention are likely due to scarring in the area of the injection site.

    I would talk to my urologist about this...there are a few new medications out, including one that has a device that implants a little pellet of mediction into the urethra, called MUSE.



    Although the picture makes most men cringe, no injection=no scarring, and it works reasonably well, too.

    Good luck; hope this helps!


    your friend,



    Steve
    Last edited by Dr Steve; 10-20-2008, 09:04 PM.

    Comment


    • #3
      Also, I just noticed that you said you couldn't get into the VA urologist until 2009...really any MD can write this stuff. The MUSE system uses the exact same medicine as the Caverject and works as well in several studies. I have written it in my office several times and I ain't no durned urologist!


      your pal,



      steve

      Comment


      • #4
        Surely there have been advances since he started this treatment.
        Are there any over the counter substitutes you'd recommend???

        Comment


        • #5
          Originally posted by ChrisTheCop View Post
          Surely there have been advances since he started this treatment.
          Are there any over the counter substitutes you'd recommend???

          The alprostadil therapy works when no other therapy will...I'm assuming he already tried Viagra and Cialis, etc. There really isn't anything over the counter that's worth much. There is this stuff called Yohimbine that is sold at health food stores as a food supplement that people have touted for years as an impotence treatment. From the medical literature:
          "The alpha-receptor antagonist yohimbine has been found to be effective in some placebo-controlled trials, but its effectiveness is probably inadequate for treatment of most ED."
          Yohimbine can cause drops in blood pressure and all kinds of weird effects, so I wouldn't recommend it, at least not unless a health care provider who knew its effects prescribed it. And why bother, then? We have other drugs that work so much better that they can prescribe.

          There's this other stuff called "Horny Goat Weed" that has not been studied well in the medical literature that is also touted. The one article I found on it said it caused mental disorders (hypomania) and fast heart beats (tachycardia). Ugh.

          Comment


          • #6
            John P Mulhall, MD MSKCC 646-422-4359

            I had prostate cancer surgery June of 2007 and have been in a penile rehab program since December of last year. I inject 10 units what Sloan Kettering calls "Bix-Mix" three times a week and take 25mg of Viagara on the off days. The hope is that the nerves will heal in time, but the continued erections save the erectile tissue from atrophy. (Awfully personal info for a message board...huh?) So here I am sixteen months later and getting a spontaneous chubby feels like a success. But there's no usable erection without injection and I have to inject whether I have sex or not...apparently erections 3 times a week are essential.

            I tell this story because the urologist that did my surgery was only concerned with getting rid of the cancer. Sexual function was a tertiary issue for him and I have to admit not being able to get an erection devasated me. ...anyway a girl I started dating is a nurse practioner and found a Dr @ Sloan Kettering who specializes in post-injury/surgery erectile dysfuntion. The first time I saw him I spent the visit crying like a baby, but the ability to have sex and just as importantly hope has been a blessing.

            The first visit was around $300 bucks and I'm sure they'd give a discount for a Veteran or make some payment arrangement. More importantly as a fellow veteran I would be willing to contribute to the cost of the visit. The medicine is cheap....about 6-8 months is $70 bucks.

            ...anyway this fellow R&F fan deserves to thanked for his willingness to speak about what most of us would fear to discuss in public.

            So, I say fuck the VA...let's get this guy an appointment with Dr Mulhall @ Sloan Kettering and we as fellow men and members should cover the cost.

            Comment


            • #7
              Originally posted by Zorro View Post
              I had prostate cancer surgery June of 2007 and have been in a penile rehab program since December of last year. I inject 10 units what Sloan Kettering calls "Bix-Mix" three times a week and take 25mg of Viagara on the off days. The hope is that the nerves will heal in time, but the continued erections save the erectile tissue from atrophy. (Awfully personal info for a message board...huh?) So here I am sixteen months later and getting a spontaneous chubby feels like a success. But there's no usable erection without injection and I have to inject whether I have sex or not...apparently erections 3 times a week are essential.

              I tell this story because the urologist that did my surgery was only concerned with getting rid of the cancer. Sexual function was a tertiary issue for him and I have to admit not being able to get an erection devasated me. ...anyway a girl I started dating is a nurse practioner and found a Dr @ Sloan Kettering who specializes in post-injury/surgery erectile dysfuntion. The first time I saw him I spent the visit crying like a baby, but the ability to have sex and just as importantly hope has been a blessing.

              The first visit was around $300 bucks and I'm sure they'd give a discount for a Veteran or make some payment arrangement. More importantly as a fellow veteran I would be willing to contribute to the cost of the visit. The medicine is cheap....about 6-8 months is $70 bucks.

              ...anyway this fellow R&F fan deserves to thanked for his willingness to speak about what most of us would fear to discuss in public.

              So, I say fuck the VA...let's get this guy an appointment with Dr Mulhall @ Sloan Kettering and we as fellow men and members should cover the cost.
              Zorro:


              Thank you for sharing your experience, and I'm glad you found something that worked for you! Do you know what's in the BixMix? I couldn't find it anywhere. Let me know and I'll try to see if it's available elsewhere as well.

              Our friend above sounds like he has severe, refractory erectile dysfunction that has responded well to the alprostadil, but with some mild distortion at the injection site. Just my opinion, but if he can get the same medication in a form that doesn't require an injection, it's at least the "devil he knows". the cool thing is that any doctor in the US with a medical license can write MUSE, so I agree, to heck with the VA at this point (unless that's his only source of medical care). Let's see what he thinks about all this. I'm in for a donation myself for a friend who's been in the service.

              thanks again,


              your friend,


              Steve

              Comment


              • #8
                Originally posted by Dr Steve View Post
                Zorro:


                Thank you for sharing your experience, and I'm glad you found something that worked for you! Do you know what's in the BixMix? I couldn't find it anywhere. Let me know and I'll try to see if it's available elsewhere as well.

                Our friend above sounds like he has severe, refractory erectile dysfunction that has responded well to the alprostadil, but with some mild distortion at the injection site. Just my opinion, but if he can get the same medication in a form that doesn't require an injection, it's at least the "devil he knows". the cool thing is that any doctor in the US with a medical license can write MUSE, so I agree, to heck with the VA at this point (unless that's his only source of medical care). Let's see what he thinks about all this. I'm in for a donation myself for a friend who's been in the service.

                thanks again,


                your friend,


                Steve
                Steve:

                It's compunded by Bryce Pharmacy in Stamford Ct and shipped to me in small foam cooler Ice Pak combo...anyway all the label says is MSK-Bimix-PAPV 30mg/Phentlmn 1mg

                ...oh and I do realize watson's circumstance is very different than mine. I guess I was just trying to commiserate with the "I've got to stick a needle in my dick" guys.

                Z...

                Comment


                • #9
                  Originally posted by Zorro View Post
                  Steve:

                  It's compunded by Bryce Pharmacy in Stamford Ct and shipped to me in small foam cooler Ice Pak combo...anyway all the label says is MSK-Bimix-PAPV 30mg/Phentlmn 1mg

                  ...oh and I do realize watson's circumstance is very different than mine. I guess I was just trying to commiserate with the "I've got to stick a needle in my dick" guys.

                  Z...
                  thanks for the information...it's some kind of proprietary mix...I may just call the pharmacy after this weekend's show and see what's in it. I'm always interested in new treatments that work.

                  Also, I hope you were cool with my comments...I wasn't bashing you at all; I appreciate all input. That's how I learn new stuff, too!

                  your friend,


                  steve

                  Comment


                  • #10
                    Ok, I called the pharmacy in Stamford, CT:

                    Bi-Mix contains:

                    30mg Papaverine
                    1mg Phentolamine

                    there's one called TRI-MIX:

                    30mg Papaverine
                    1mg Phentolamine
                    10mcg Prostaglandin E1

                    This Bryce Laboratories is a "compounding pharmacy" and they make all kinds of interesting products. All of these are administered by injection into the penis. One thing I learned is that there are lots and lots of alternatives for erectile dysfunction, if you're willing to inject your schlong with medicine. Honestly, I was only aware of papaverine and alprostadil.

                    For those who are interested, here's just one of a million articles on this subject in the literature:

                    J Sex Med. 2004 Nov;1(3):310-3.

                    Intracavernous chlorpromazine versus phentolamine: a double-blind clinical
                    comparative study.


                    Shamloul R, El-Dakhly M, Ghanem H, Gadallah A, Mokhtar H.

                    Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt.
                    rannone74@hotmail.com

                    INTRODUCTION: Intracavernous pharmacotherapy is one of the most common treatment
                    modalities of erectile dysfunction (ED). There are different drugs that are used
                    for intracavernous injection including papaverine, phentolamine, prostaglandins
                    E1, phenoxybenzamine, and moxisylate.
                    AIM: The aim of this study is to evaluate
                    the efficacy of chlorpromazine as an intracavernous vasoactive agent alone or
                    with other drugs. METHODS: This study was performed on 50 patients presenting to
                    our department complaining of ED. Patients were divided into three groups
                    according to the type of intracavernous drug injected. Group A included 20
                    patients who received an intracavernous injection of 1 mL bimix (30 mg papaverine
                    + 1 mg phentolamine) followed a week later by intracavernous test dose using a 1
                    mL mixture of papaverine and chlorpromazine (30 mg papaverine + 2.5 mg
                    chlorpromazine). Group B included 20 patients who received an intracavernous
                    injection of 1 mL trimix (30 mg papaverine + 1 mg phentolamine + 10 microg PGE1).
                    A week later they received another intracavernous test dose using a 1 mL mixture
                    of papaverine, PGE1, and chlorpromazine (30 mg papaverine + 2.5 mg chlorpromazine
                    + 10 microg PGE1). Group C included 10 patients who received various
                    intracavernous injections of chlorpromazine in doses 1 mg, 2 mg, 5 mg, and 10 mg.
                    RESULTS: There was no significant difference in erection response and erection
                    duration between phentolamine and chlorpromazine. Prolonged erection occurred in
                    two patients of group B and postural hypotension occurred in three patients of
                    group C. CONCLUSION: Chlorpromazine can be used as an intracavernous vasoactive
                    agent; it is similar to phentolamine in efficacy and short-term side effect
                    profile.



                    Thanks for prodding me to learn more; it's amazing how much there is out there...I feel like my knowledge base is pretty broad but after all this time I'm still always finding new info out there! One of the things that makes this constantly interesting.

                    Thanks again,


                    your pal,


                    steve
                    Last edited by Dr Steve; 10-23-2008, 03:03 PM.

                    Comment


                    • #11
                      Originally posted by Dr Steve View Post
                      Ok, I called the pharmacy in Stamford, CT:

                      Bi-Mix contains:

                      30mg Papaverine
                      1mg Phentolamine

                      there's one called TRI-MIX:

                      30mg Papaverine
                      1mg Phentolamine
                      10mcg Prostaglandin E1

                      This Bryce Laboratories is a "compounding pharmacy" and they make all kinds of interesting products. All of these are administered by injection into the penis. One thing I learned is that there are lots and lots of alternatives for erectile dysfunction, if you're willing to inject your schlong with medicine. Honestly, I was only aware of papaverine and alprostadil.

                      For those who are interested, here's just one of a million articles on this subject in the literature:

                      J Sex Med. 2004 Nov;1(3):310-3.

                      Intracavernous chlorpromazine versus phentolamine: a double-blind clinical
                      comparative study.


                      Shamloul R, El-Dakhly M, Ghanem H, Gadallah A, Mokhtar H.

                      Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt.
                      rannone74@hotmail.com

                      INTRODUCTION: Intracavernous pharmacotherapy is one of the most common treatment
                      modalities of erectile dysfunction (ED). There are different drugs that are used
                      for intracavernous injection including papaverine, phentolamine, prostaglandins
                      E1, phenoxybenzamine, and moxisylate.
                      AIM: The aim of this study is to evaluate
                      the efficacy of chlorpromazine as an intracavernous vasoactive agent alone or
                      with other drugs. METHODS: This study was performed on 50 patients presenting to
                      our department complaining of ED. Patients were divided into three groups
                      according to the type of intracavernous drug injected. Group A included 20
                      patients who received an intracavernous injection of 1 mL bimix (30 mg papaverine
                      + 1 mg phentolamine) followed a week later by intracavernous test dose using a 1
                      mL mixture of papaverine and chlorpromazine (30 mg papaverine + 2.5 mg
                      chlorpromazine). Group B included 20 patients who received an intracavernous
                      injection of 1 mL trimix (30 mg papaverine + 1 mg phentolamine + 10 microg PGE1).
                      A week later they received another intracavernous test dose using a 1 mL mixture
                      of papaverine, PGE1, and chlorpromazine (30 mg papaverine + 2.5 mg chlorpromazine
                      + 10 microg PGE1). Group C included 10 patients who received various
                      intracavernous injections of chlorpromazine in doses 1 mg, 2 mg, 5 mg, and 10 mg.
                      RESULTS: There was no significant difference in erection response and erection
                      duration between phentolamine and chlorpromazine. Prolonged erection occurred in
                      two patients of group B and postural hypotension occurred in three patients of
                      group C. CONCLUSION: Chlorpromazine can be used as an intracavernous vasoactive
                      agent; it is similar to phentolamine in efficacy and short-term side effect
                      profile.



                      Thanks for prodding me to learn more; it's amazing how much there is out there...I feel like my knowledge base is pretty broad but after all this time I'm still always finding new info out there! One of the things that makes this constantly interesting.

                      Thanks again,


                      your pal,


                      steve
                      Steve:

                      I was tested with 10 units of the Tri-Mix and that was too much. 8 kept things up a little too long as well. It was finally decided they would cut back to 8 units of Bi-Mix...which was later increased to 10. that's my current dosage.

                      It's a diabetic needle and yes it is uncomfortable, but the alternative...well nuff said there.

                      But luckily there's humor in every situation. I had told the story to a friend and he suggested anbesol on the injection site. Seemed like a great idea tried it and while I was with my chick she stops...gets a really odd look and says I don't know why, but my lips are numb.

                      Z

                      Comment


                      • #12
                        Originally posted by Zorro View Post
                        Seemed like a great idea tried it and while I was with my chick she stops...gets a really odd look and says I don't know why, but my lips are numb.

                        Z

                        Comment


                        • #13
                          This isn't a question.

                          Please make the thought of injecting medicine in the base of the penis go away.

                          Comment


                          • #14
                            how to use caverject?

                            Hi.
                            I have had surgery on prostacacancer 1997.
                            Have met at woman lately and started to search for way to get ejection
                            This matter is about caverject.
                            I have tried Caverject 12 times.
                            Five times I got enough erection.

                            I think that my problem is that sometimes my penis is to small to find the right place to insert the needle
                            If I try to masturbate a little it gets enough big to insert the needle in the right place.
                            I have met my new woman twice ( she lives far away from me) and both times
                            I could not masturbate to make penis a bit bigger. So there was difficult to hit the right place for injection. I took a chance with 5 mikrogram but it did not get right and the ejection went to small. When you do not hit the right place in penis you ought maybee better use 20 microgram.

                            So my problem is the I do not know whether to use 5 microgram or 20. It depend where on penis I insert. I am thankful for advice. maybee there is a work-around?
                            Ziggys
                            ps: My new woman likes me very much so fortunately I will get new chances

                            Comment


                            • #15
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