RonFez.net Messageboard - View Single Post - Caverject = Injections in the Penis for Impotence

Dr Steve · 10-23-2008, 10:00 AM

Ok, I called the pharmacy in Stamford, CT:

Bi-Mix contains:

30mg Papaverine
1mg Phentolamine

there's one called TRI-MIX:

30mg Papaverine
1mg Phentolamine
10mcg Prostaglandin E1

This Bryce Laboratories is a "compounding pharmacy" and they make all kinds of interesting products. All of these are administered by injection into the penis. One thing I learned is that there are lots and lots of alternatives for erectile dysfunction, if you're willing to inject your schlong with medicine. Honestly, I was only aware of papaverine and alprostadil.

For those who are interested, here's just one of a million articles on this subject in the literature:

J Sex Med. 2004 Nov;1(3):310-3.

Intracavernous chlorpromazine versus phentolamine: a double-blind clinical
comparative study.

Shamloul R, El-Dakhly M, Ghanem H, Gadallah A, Mokhtar H.

Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt.
rannone74@hotmail.com

INTRODUCTION: Intracavernous pharmacotherapy is one of the most common treatment
modalities of erectile dysfunction (ED). There are different drugs that are used
for intracavernous injection including papaverine, phentolamine, prostaglandins
E1, phenoxybenzamine, and moxisylate. AIM: The aim of this study is to evaluate
the efficacy of chlorpromazine as an intracavernous vasoactive agent alone or
with other drugs. METHODS: This study was performed on 50 patients presenting to
our department complaining of ED. Patients were divided into three groups
according to the type of intracavernous drug injected. Group A included 20
patients who received an intracavernous injection of 1 mL bimix (30 mg papaverine
+ 1 mg phentolamine) followed a week later by intracavernous test dose using a 1
mL mixture of papaverine and chlorpromazine (30 mg papaverine + 2.5 mg
chlorpromazine). Group B included 20 patients who received an intracavernous
injection of 1 mL trimix (30 mg papaverine + 1 mg phentolamine + 10 microg PGE1).
A week later they received another intracavernous test dose using a 1 mL mixture
of papaverine, PGE1, and chlorpromazine (30 mg papaverine + 2.5 mg chlorpromazine
+ 10 microg PGE1). Group C included 10 patients who received various
intracavernous injections of chlorpromazine in doses 1 mg, 2 mg, 5 mg, and 10 mg.
RESULTS: There was no significant difference in erection response and erection
duration between phentolamine and chlorpromazine. Prolonged erection occurred in
two patients of group B and postural hypotension occurred in three patients of
group C. CONCLUSION: Chlorpromazine can be used as an intracavernous vasoactive
agent; it is similar to phentolamine in efficacy and short-term side effect
profile.

Thanks for prodding me to learn more; it's amazing how much there is out there...I feel like my knowledge base is pretty broad but after all this time I'm still always finding new info out there! One of the things that makes this constantly interesting.

Thanks again,

your pal,

steve

10-23-2008, 10:00 AM	#10
Dr Steve Weird Medicine Forum Moderator Click here to ask Dr. Steve a question! Turd of a Mod I can't seem to get hard Join Date: Sep 2005 Location: Tennessee Posts: 1,233	Ok, I called the pharmacy in Stamford, CT: Bi-Mix contains: 30mg Papaverine 1mg Phentolamine there's one called TRI-MIX: 30mg Papaverine 1mg Phentolamine 10mcg Prostaglandin E1 This Bryce Laboratories is a "compounding pharmacy" and they make all kinds of interesting products. All of these are administered by injection into the penis. One thing I learned is that there are lots and lots of alternatives for erectile dysfunction, if you're willing to inject your schlong with medicine. Honestly, I was only aware of papaverine and alprostadil. For those who are interested, here's just one of a million articles on this subject in the literature: J Sex Med. 2004 Nov;1(3):310-3. Intracavernous chlorpromazine versus phentolamine: a double-blind clinical comparative study. Shamloul R, El-Dakhly M, Ghanem H, Gadallah A, Mokhtar H. Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt. rannone74@hotmail.com INTRODUCTION: Intracavernous pharmacotherapy is one of the most common treatment modalities of erectile dysfunction (ED). There are different drugs that are used for intracavernous injection including papaverine, phentolamine, prostaglandins E1, phenoxybenzamine, and moxisylate. AIM: The aim of this study is to evaluate the efficacy of chlorpromazine as an intracavernous vasoactive agent alone or with other drugs. METHODS: This study was performed on 50 patients presenting to our department complaining of ED. Patients were divided into three groups according to the type of intracavernous drug injected. Group A included 20 patients who received an intracavernous injection of 1 mL bimix (30 mg papaverine + 1 mg phentolamine) followed a week later by intracavernous test dose using a 1 mL mixture of papaverine and chlorpromazine (30 mg papaverine + 2.5 mg chlorpromazine). Group B included 20 patients who received an intracavernous injection of 1 mL trimix (30 mg papaverine + 1 mg phentolamine + 10 microg PGE1). A week later they received another intracavernous test dose using a 1 mL mixture of papaverine, PGE1, and chlorpromazine (30 mg papaverine + 2.5 mg chlorpromazine + 10 microg PGE1). Group C included 10 patients who received various intracavernous injections of chlorpromazine in doses 1 mg, 2 mg, 5 mg, and 10 mg. RESULTS: There was no significant difference in erection response and erection duration between phentolamine and chlorpromazine. Prolonged erection occurred in two patients of group B and postural hypotension occurred in three patients of group C. CONCLUSION: Chlorpromazine can be used as an intracavernous vasoactive agent; it is similar to phentolamine in efficacy and short-term side effect profile. Thanks for prodding me to learn more; it's amazing how much there is out there...I feel like my knowledge base is pretty broad but after all this time I'm still always finding new info out there! One of the things that makes this constantly interesting. Thanks again, your pal, steve __________________ Be sure you check out anything you read here with your regular health care provider. "Credo Che Tutti gli Uomini Siano Fratelli" Doctor Steve: Vintner to the Stars http://www.doctorsteve.com Last edited by Dr Steve; 10-23-2008 at 10:03 AM.